AustralieFrV1, Main, Exploration, bibRecord, 005A20

Outcomes from the REACH Registry for Australian general practice patients with or at high risk of atherothrombosis

Identifieur interne : 005A20 ( Main/Exploration ); précédent : 005A19; suivant : 005A21

Outcomes from the REACH Registry for Australian general practice patients with or at high risk of atherothrombosis

Auteurs : Christopher M. Reid [Australie] ; Zanfina Ademi [Australie] ; Mark R. Nelson [Australie] ; Greg Connor [Australie] ; Derek P. Chew [Australie] ; Louise Shiel [Australie] ; Ana Smeath [Australie] ; Fred De Looze [Australie] ; Ph Gabriel Steg [France] ; Deepak L. Bhatt [États-Unis] ; Danny Liew [Australie]

Source :

Medical journal of Australia [ 0025-729X ] ; 2012.

RBID : Pascal:12-0123183

Descripteurs français

Pascal (Inist)
- Thrombose, Evolution, Pronostic, Athérosclérose, Registre, Australie, Médecine générale, Homme, Malade, Risque élevé.
Wicri :
- geographic : Australie.
- topic : Médecine générale, Homme.

English descriptors

KwdEn :
- Atherosclerosis, Australia, Evolution, General practice, High risk, Human, Patient, Prognosis, Register, Thrombosis.

Abstract

Objective: To report on 1-year cardiovascular (CV) event rates in patients with established cardiovascular disease (CVD) or with multiple cardiovascular risk factors. Design, patients and setting: Prospective cohort study of 2873 patients at high risk of atherothrombosis based on the presence of multiple risk factors and overt coronary artery disease (CAD), cerebrovascular disease (CerVD) or peripheral arterial disease (PAD) presenting to 273 Australian general practitioners; this study was conducted as part of the international REACH Registry. Main outcome measures: One-year rates of cardiovascular death, myocardial infarction, stroke, and hospitalisation for cardiovascular procedures. Results: The cardiovascular death rate at 1 year was 1.4%. The combined cardiovascular death, non-fatal MI, stroke and hospitalisation rate for vascular disease affecting one location at 1 year was 11%. Even for patients with no overt disease, but with multiple risk factors, the 1-year combined event rate was 4.2%. The highest combined event rate was in patients with PAD (21.0%), and in patients with atherothrombotic disease identified in all three locations (coronary arteries, cerebrovascular system and peripheral arteries) at 39%. Conclusion: The rate of clinical events in community-based patients with stable atherothrombotic disease increases dramatically with the severity of disease and the number of vascular beds involved. Where disease was evident in all three locations, and for patients with PAD alone, the 1-year risk of cardiovascular events was substantially increased. Poor adherence to statin therapy in the secondary preventive setting is a major treatment gap that needs to be closed; the influences of obesity and diabetes warrant further investigation.

Affiliations:

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Objective: To report on 1-year cardiovascular (CV) event rates in patients with established cardiovascular disease (CVD) or with multiple cardiovascular risk factors. Design, patients and setting: Prospective cohort study of 2873 patients at high risk of atherothrombosis based on the presence of multiple risk factors and overt coronary artery disease (CAD), cerebrovascular disease (CerVD) or peripheral arterial disease (PAD) presenting to 273 Australian general practitioners; this study was conducted as part of the international REACH Registry. Main outcome measures: One-year rates of cardiovascular death, myocardial infarction, stroke, and hospitalisation for cardiovascular procedures. Results: The cardiovascular death rate at 1 year was 1.4%. The combined cardiovascular death, non-fatal MI, stroke and hospitalisation rate for vascular disease affecting one location at 1 year was 11%. Even for patients with no overt disease, but with multiple risk factors, the 1-year combined event rate was 4.2%. The highest combined event rate was in patients with PAD (21.0%), and in patients with atherothrombotic disease identified in all three locations (coronary arteries, cerebrovascular system and peripheral arteries) at 39%. Conclusion: The rate of clinical events in community-based patients with stable atherothrombotic disease increases dramatically with the severity of disease and the number of vascular beds involved. Where disease was evident in all three locations, and for patients with PAD alone, the 1-year risk of cardiovascular events was substantially increased. Poor adherence to statin therapy in the secondary preventive setting is a major treatment gap that needs to be closed; the influences of obesity and diabetes warrant further investigation.</div>
</front>
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<country name="États-Unis"><noRegion><name sortKey="Bhatt, Deepak L" sort="Bhatt, Deepak L" uniqKey="Bhatt D" first="Deepak L." last="Bhatt">Deepak L. Bhatt</name>
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Serveur d'exploration sur les relations entre la France et l'Australie

Outcomes from the REACH Registry for Australian general practice patients with or at high risk of atherothrombosis

Outcomes from the REACH Registry for Australian general practice patients with or at high risk of atherothrombosis

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri